ARTICLE
In patients with chronic nonspecific low back pain (NCLBP), brain function changes due to the neuroplastic changes in different regions. This study aimed to evaluate the brain metabolite changes after spinal manipulation. After treatment, severity of pain and functional disability were significantly reduced in the treatment group vs. sham group. In the patient with low back pain, spinal manipulation affects the central nervous system and changes the brain metabolites. Consequently, pain and functional disability are reduced. Nonspecific chronic low back pain (NCLBP) is common disease in the lumbar area without any neurologic signs and specific reasons. NCLBP accounts for 90% of the chronic low back pain (CLBP) cases. Studies have shown that CLBP causes central sensitization, and patients with CLBP are hypersensitive to painful stimuli due to neuroplastic changes. To treat and resolve issues associated with NCLBP, medical treatments and physiotherapy are recommended. Their purpose is to reduce pain and disability caused by NCLBP. Spinal manipulation is a successful, cost-effective, and non-invasive treatment for NCLBP. Researches have confirmed the effect of manipulation on function improvement and pain reduction in patients with NCLBP. The neurophysiological mechanism of manipulation refers to the ability of the central nervous system to modulate sensory information. Source: https://chiro.org/wordpress/2019/12/the-effect-of-spinal-manipulation-on-brain-neurometabolites-in-chronic-nonspecific-low-back-pain-patients/